Dr TENG, Jade Lee Lee

 

BSc, PhD

 

Scientific Officer, Department of Microbiology

 

Email: llteng@hku.hk

 

ORCID : https://orcid.org/0000-0002-3912-4057

 

 

Research Interests:

Emerging infectious diseases
Novel microbes discovery
Microbial genomics
Clinical diagnostics

 

Representative publications:

1. Teng JL, Woo PC, Leung KW, Lau SK, Wong MK, Yuen KY. Pseudobacteraemia in a patient with neutropenic fever caused by a novel paenibacillus species: Paenibacillus hongkongensis sp. nov. Mol Pathol. 2003 Feb;56(1):29-35.
 

2. Teng JL, Woo PC, Ma SS, Sit TH, Ng LT, Hui WT, Lau SK, Yuen KY. Ecoepidemiology of Laribacter hongkongensis, a novel bacterium associated with gastroenteritis. J Clin Microbiol. 2005 Feb;43(2):919-22.
 

3. Woo PC, Lau SK, Teng JL, Yuen KY. Current status and future directions for Laribacter hongkongensis, a novel bacterium associated with gastroenteritis and traveller's diarrhoea. Curr Opin Infect Dis. 2005 Oct;18(5):413-9.
 

4. Woo PC, Teng JL, Lau SK, Yuen KY. Clinical, phenotypic, and genotypic evidence for Streptococcus sinensis as the common ancestor of anginosus and mitis groups of streptococci. Med Hypotheses. 2006;66(2):345-51.
 

5. Woo PC, Teng JL, Ma SS, Lau SK, Yuen KY. Characterization of a novel cryptic plasmid, pHLHK26, in Laribacter hongkongensis. New Microbiol. 2007 Apr;30(2):139-47.
 

6. Woo PC, Lau SK, Teng JL, Tse H, Yuen KY. Then and now: use of 16S rDNA gene sequencing for bacterial identification and discovery of novel bacteria in clinical microbiology laboratories. Clin Microbiol Infect. 2008 Oct;14(10):908-34.
 

7. Woo PC, Teng JL*, Tsang AK, Tse H, Tsang VY, Chan KM, Lee EK, Chan JK, Ma SS, Tam DM, Chung LM, Lau SK, Yuen KY. Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea. BMC Microbiol. 2009 Jan 30;9:21.
 

8. Woo PC, Lau SK, Tse H, Teng JL*, Curreem SO, Tsang AK, Fan RY, Wong GK, Huang Y, Loman NJ, Snyder LA, Cai JJ, Huang JD, Mak W, Pallen MJ, Lok S, Yuen KY. The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats. PLoS Genet. 2009 Mar;5(3):e1000416.
 

9. Woo PC, Teng JL*, Tsang SN, Tse CW, Lau SK, Yuen KY. The oral cavity as a natural reservoir for Streptococcus sinensis. Clin Microbiol Infect. 2008 Nov;14(11):1075-9.
 

10. Woo PC, Teng JL*, Wu JK, Leung FP, Tse H, Fung AM, Lau SK, Yuen KY. Guidelines for interpretation of 16S rRNA gene sequence-based results for identification of medically important aerobic Gram-positive bacteria. J Med Microbiol. 2009 Aug;58(Pt 8):1030-6.
 

11. Woo PC, Teng JL*, Lam KK, Tse CW, Leung KW, Leung AW, Lau SK, Yuen KY. First report of Gordonibacter pamelaeae bacteremia. J Clin Microbiol. 2010 Jan;48(1):319-22.
 

12. Woo PC, Wong SS, Teng JL*, Leung KW, Ngan AH, Zhao DQ, Tse H, Lau SK, Yuen KY. Leptotrichia hongkongensis sp. nov., a novel Leptotrichia species with the oral cavity as its natural reservoir. J Zhejiang Univ Sci B. 2010 Jun;11(6):391-401.
 

13. Woo PC, Teng JL*, Yeung JM, Tse H, Lau SK, Yuen KY. Automated identification of medically important bacteria by 16S rRNA gene sequencing using a novel comprehensive database, 16SpathDB. J Clin Microbiol. 2011 May;49(5):1799-809.
 

14. Teng JL, Yeung MY, Yue G, Au-Yeung RK, Yeung EY, Fung AM, Tse H, Yuen KY, Lau SK, Woo PC. In silico analysis of 16S rRNA gene sequencing based methods for identification of medically important aerobic Gram-negative bacteria. J Med Microbiol. 2011 Sep;60(Pt 9):1281-6.
 

15. Wong SS, Teng JL*, Poon RW, Choi GK, Chan KH, Yeung ML, Hui JJ, Yuen KY. Comparative evaluation of a point-of-care immunochromatographic test SNAP 4Dx with molecular detection tests for vector-borne canine pathogens in Hong Kong. Vector Borne Zoonotic Dis. 2011 Sep;11(9):1269-77.
 

16. Teng JL, Ho CC, Yeung RS, Wong AY, Wang H, Chen C, Yuen KY, Lau SK, Woo PC. Evaluation of 16SpathDB 2.0, an automated comprehensive database for identification of medically important bacteria by 16S rRNA gene sequencing, using 689 complete bacterial genomes. Diagn Microbiol Infect Dis. 2014 Feb;78(2):105-15.
 

17. Xiong L, Teng JL*, Watt RM, Kan B, Lau SK, Woo PC. Arginine survival in Laribacter hongkongensis: a possible result of arc gene cassette duplication. BMC Microbiol. 2014 Feb 17;14(1):42.
 

18. Woo PC, Lau SK, Teng JL*, Tsang AK, Joseph M, Wong EY, Tang Y, Sivakumar S, Xie J, Bai R, Wernery R, Wernery U, Yuen KY. New Hepatitis E Virus Genotype in Camel, the Middle East. Emerg Infect Dis. 2014 Jun;20(6):1044-8
 

19. Teng JL, Huang Y, Tse H, Chen JH, Tang Y, Lau SK, Woo PC. Phylogenomic and MALDI-TOF MS analysis of Streptococcus sinensis HKU4T reveals a distinct phylogenetic clade of the genus Streptococcus. Genome Biol Evol. 2014 Oct 20;6(10):2930-43.
 

20. Woo PC, Lau SK, Teng JL*, Tsang AK, Joseph M, Wong EY, Tang Y, Sivakumar S, Bai R, Wernery R, Wernery U, Yuen KY. Metagenomic analysis of viromes of dromedary camel fecal samples reveals large number and high diversity of circoviruses and picobirnaviruses. Virology. 2014 Dec;471-473:117-25.
 

21. Lau SK, Wu AK, Teng JL*, Tse H, Curreem SO, Tsui SK, Huang Y, Chen JH, Lee RA, Yuen KY, Woo PC. Evidence for Elizabethkingia anophelis transmission from mother to infant, Hong Kong. Emerg Infect Dis. 2015 Feb;21(2):232-41.
 

22. Lau SK, Teng JL*, Huang Y, Curreem SO, Tsui SK, Woo PC. Draft Genome Sequence of bacteremic isolate Catabacter hongkongensis type strain HKU16T. Genome Announc. 2015 May 21;3(3). pii: e00531-15.
 

23. Woo PC, Lau SK, Teng JL*, Tsang AK, Joseph S, Xie J, Jose S, Fan RY, Wernery U, Yuen KY. A novel astrovirus from dromedaries in the Middle East. J Gen Virol. 2015 Sep;96(9):2697-707.
 

24. Xiong L, Teng JL*, Watt RM, Liu C, Lau SK, Woo PC Molecular characterization of arginine deiminase pathway in Laribacter hongkongensis and unique regulation of arginine catabolism and anabolism by multiple environmental stresses. Environ Microbiol. 2015 Nov;17(11):4469-83.
 

25. Teng JL, Tang Y, Ngan AH, Huang Y, Tsang CC, Choi GK, Lau SK, Woo PC. Tsukamurella hongkongensis sp. nov. and Tsukamurella sinensis sp. nov. isolated from patients with keratitis, catheter-related bacteremia and conjunctivitis in Hong Kong. Int J Syst Evol Microbiol. 2016 Jan;66(1):391-7.
 

26. Xiong L, Teng JL*, Betelho MG, Lo RC, Lau SK, Woo PC. Janus Faces of Arginine Metabolism in Health: Bacterial Pathogenesis and Cancer Therapy. Int J Mol Sci. 2016 Mar 11;17(3).
 

27. Tang Y, Teng JL*, Cheung CL, Ngan AH, Huang Y, Wong SS, Yip EK, Ng KH, Que TL, Lau SK, Woo PC. Tsukamurella serpentis sp. nov., isolated from the oral cavity of Chinese cobras (Naja atra) in Hong Kong. Int J Syst Evol Microbiol. 2016 Sep;66(9):3329-3336.
 

28. Teng JL, Tang Y, Huang Y, Chen JH, Wong SS, Lau SK, Woo PC. Phylogenomic analyses and reclassification of species within the genus Tsukamurella: Insights to species definition in the post-genomic era. Front Microbiol. 2016 Jul 21;7:1137.
 

29. Woo PC, Lau SK, Teng JL*, Cao KY, Wernery U, Schountz, Chiu TH, Tsang AK, Wong PC, Wong YM, Yuen KY. New Hepatitis E Virus Genotype in Bactrian Camels, Xinjiang, China, 2013. Emerg Infect Dis. 2016 Dec;22(12):2219-2221.
 

30. Woo PC, Teng JL*, Ru B, Wong AY, Martelli P, Hui SW, Tsang AK, Lau CC, Ahmed SS, Yip CC, Choi GK, Li KS, Lam CS, Lau SK, Yuen KY. High diversity of genogroup I picobirnaviruses in mammals. Front Microbiol. 2016 Nov 23;7:1886.
 

31. Teng JL, Tang Y, Chiu TH, Cheung CL, Ngan AH, Ngai C, Wong SS, Que TL, Lau SK, Woo PC. groEL gene is a promising target for species identification of Tsukamurella. J Clin Microbiol. 2017 Feb;55(2):649-653.
 

32. Teng JL, Tang Y, Lau SK, Woo PC. Reply to Perez del Molino Bernal and Agüero Balbin, "secA1 Is a Useful Target for Identification of Tsukamurella pulmonis". J Clin Microbiol. 2017 May;55(5):1592-1594.
 

33. Teng JL, Yeung ML, Chan E, Jia L, Lin CH, Huang Y, Tse H, Wong SS, Shan PC, Lau SK, Woo PC. PacBio but not Illumina technology can achieve fast, accurate and complete closure of the high GC, complex Burkholderia pseudomallei two-chromosome genome. Front Microbiol. 2017 Aug 2;8:1448.
 

34. Teng JL, Tang Y, Chiu TH, Zhao Z, Chan E, Ngan AH, Ngai C, Wong SS, Lau SK, Woo PC. Tsukamurella ocularis sp. nov. and Tsukamurella hominis sp. nov. isolated from patients with conjunctivitis in Hong Kong. Int J Syst Evol Microbiol. 2018 Mar;68(3):810-818.
 

35. Lau SK, Teng JL*, Chiu TH, Chan E, Tsang AK, Panagiotou G, Zhai SL, Woo PC. Differential microbial communities of omnivorous and herbivorous cattle in Southern China. Comput Struct Biotechnol J. 2018 Feb 15;16:54-60.
 

36. Teng JL, Tang Y, Wong SS, Fong JY, Zhao Z, Wong CP, Chen JH, Ngan AH, Wu AK, Fung KS, Que TL, Lau SK, Woo PC. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for identification of Tsukamurella species: Tsukamurella tyrosinosolvens as the predominant species associated with ocular infections. Emerg Microbes Infect. 2018 May 9;7(1):80
 

37. Teng JL, Martelli P, Chan WM, Lee HH, Hui SW, Lau CC, Tse H, Yuen KY, Lau SK, Woo PC. Two novel noroviruses and a novel norovirus genogroup in California sea lions. J Gen Virol. 2018 Jun;99(6):777-782.
 

38. Guan TP, Teng JL*, Yeong KY, You ZQ, Liu Hao, Wong SS, Lau SK, Woo PC. Metagenomic analysis of Sichuan takin fecal sample viromes reveals novel enterovirus and astrovirus. Virology. 2018 Jun 7;521:77-91.

*Equal contribution as co-first authors.